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Learn how you can help address the opioid crisis from home.


Combating Indiana’s
opioid crisis.

The Rx Abuse Leadership Initiative (RALI) Indiana
is a diverse coalition of business and community
leaders who are boosting the fight against Indiana’s opioid epidemic. Together, we can keep Hoosiers safe from the threat of addiction.

About Us


The Rx Abuse Leadership Initiative (RALI) Indiana is working alongside state leaders to combat this problem.

RALI Indiana will help those facing addiction in urban and rural communities, educate Hoosiers about the importance of safe disposal of unused Rx medication, and help Indiana employers de-stigmatize addiction and improve the health of Indiana's workforce.

Making a Difference


Click the images below to learn more about the partners of RALI Indiana:


The Wellness Council of Indiana aims to protect Indiana’s workforce by providing tools to

local businesses and individuals affected by

drug abuse. Click HERE to read more about this organization and the resources they provide to Indiana employers.

Have an organization, event or individual making a difference
in the fight against opioid misuse?
Let us know by filling out the short form below.

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Safe Use and Disposal


Everyone can play a role in helping prevent addiction and
prescription drug misuse by safely using, storing and

disposing of prescription medications.

  • Always talk to your doctor about how to use a prescription medication before taking it.

  • Be sure to follow dosing recommendations


  • Don't mix medications without first checking with your doctor. Never mix prescription opioids with alcohol.


  • Don’t take someone else’s medication.


  • Always keep prescription medications in a locked or secure place– and always out of the reach of children.

  • Have a family conversation about the dangers of misusing prescription medication.

  • Never share medications with family members.



  • Once you are finished  using a prescription  medication as directed by a medical professional, you  should safely dispose  of it rather than keep it in your medicine cabinet for future use.

  • There are several ways to easily and safely dispose of unused medications right at home. Learn more below.


You can use household materials to dispose of your unused medications. All you have to do is mix your medicines with kitty litter or old coffee grounds in an airtight container and dispose of it in your trash can. 

You can visit a drug takeback center in your community. 

Click HERE to find locations in Indiana.

You can use a home disposal kit - available from several sources including RALI partners - you'll put unused medications in the included pouch, add water, seal and dispose of it in the trash.

Warning Signs


If someone you know has started misusing opioids, early intervention is important. Learning the warning signs of opioid addiction can help protect your family, friends and communities.

Physical and behavioral changes could indicate someone is misusing prescription opioids or illegal drugs, like heroin or fentanyl.

Common signs of opioid misuse:



Physical Signs:

  • Increase in fatigue or drowsiness

  • Rapid weight loss

  • Frequent constipation or nausea

  • Decline in personal hygiene

  • Wearing long sleeves regardless of the season


Behavioral Signs:

  • Unexplained absences from school or work

  • Drop in grades or performance at work

  • Loss of interest in hobbies

  • Spending less time with friends or family

  • Hanging out with a new friend group


Indicators in the Home:

  • Missing prescription medications

  • Empty pill bottles

  • Paraphernalia, such as syringes, shoelaces or rubber hose, kitchen spoons, aluminum foil, straws, lighters

Spotting warning signs in teenagers can be particularly hard because young people go through many emotional and physical changes.

If you suspect a loved one is misusing opioids, there are resources that can help you prepare for a conversation with them.  It’s also important to talk to your family doctor about prevention and treatment options.

Indiana residents can find extensive information about opioids including prevention strategies and treatment options available across Indiana on the state’s “Know the O” site.

Additionally, resources are available from:

News and Updates


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